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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c68dcd78c64308bad03b0917693784d485fe096b60405e4607d08782210c46c8' 
  AND token = 'RQE0QszkPOXO0vqw49Bz4jDU7ZXG/lgVR8z2FZMoxDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}