SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '486efa6d4660ed262f010e0a32379e837a9ec54d4c4fa49560669074c1e7c05f' 
  AND token = 'YXH3i43PhhHCraMNZQvkXEb/uFRfHieOCU53o8pGopo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}