SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df7ae66b383b0ca41b5f50d4c84b5a885baf4b2226e6072f71f36d58ce210f16' 
  AND token = 'q4wx9TzvDEuS44LVJUxWexRk9wVgvU7hNRX5LV6EiJE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}