SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e98f06b2d30bd2a381893bcccffdff02e88960c367da607a1719a57ebaff85d6' 
  AND token = 'BcLK+EZT/NFZJpaL1Xn2/LHgwUWfJzQtGd6Cc3TYaF0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00079

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}