SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '194232c26bf1dff977f6505486aeb8bd386398e0e8c927c22acd9993d474c426' 
  AND token = '3SAIywVEf2U+5w/5zposkOYzadgvJ57vIt3/E9/DFAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}