SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bfc9edbdfb49b14173c9865a7552229e0dd31af3ea3dbe54f5cb2a226a87b6f' 
  AND token = '6ec5DJI4nj++676SoDf6n0IsYGsbnZQv5HYgODN/DVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}