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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acaef5dc1e0b5ba554e3dfa5e0ee4058f062ea1519d2ba1541df277d4e13c316' 
  AND token = 'iaCEzhX4zPm+UmgLZ65u5A75+LXrp1GNOPywL+dzqhM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}