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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0dbd7d977b27a6d525b21c69f1d73f44c2e766df79296abf358674ef5aa5ed6c' 
  AND token = 'KC9L450aXsOBs1uXEFdLYO3KgHLbictuSlRsKRW9EwI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}