SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '737c1c3414f00c041a17f6bf636b9d2460c294d3db34fcaaa8031f37b0df4706' 
  AND token = 'aPis1+HXHQj2I1RUlqAGwMGK69bF/yZdhwTUCURic34=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}