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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fed65d1877b5d7d14896f0ca6690ce0c6b0fe221311f4c225772f2641046a2da' 
  AND token = 'vFn7FoJqB09YsBLoUyjYDewdFIkNyjgq7bKuuZRjgfI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}