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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '040176e4302e89abb9b0706d7a259c7c666e5f6b8b0954af9b67719ad8a4f629' 
  AND token = 'tUDmAQrtL+QpyG5L5Iw7as24wlpGVkXLk70p21M0R9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00064

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}