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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e3b213c9f32a9d507e23b8ae7d3c546f8203b1fdf7114214480652550603d4d' 
  AND token = '9ruSmRsgEbz0dITt5A6Si63k/tbuX2+mSn34bHTcDIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}