SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '777af957b314417fa7648bba8c20ee3f17b78e5bacca179c9c6d383a43b36a7f' 
  AND token = 'J5l1S6PgyAbd3ityz6Oo6hx9UulijK6JxS5/AF/02CQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}