SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a83df2fabc06e98d8050e72578d43f7fc210438b7666941bbe6f8a7b6fa6f662' 
  AND token = 'eWXJ+9xAfAeU45KfdRjhcBgflONWUpRuXL3JdK/2oQQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}