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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22ccbabbf1d91430f7a13c4097a593a44ef4fc3db78beed623a04e37b03da389' 
  AND token = 'nyHmvOMeHfpBF++hWdt5uxJvwOSAURE0Kbg/Eu3U0i0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}