SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ad4d4bd3d9148fafc3838b395c46580556ea14d383cdc4581ba34cc1027d51d' 
  AND token = '1r+jEEk5ZyEt5+HiCOWXadmApHJzRc5dJMNbDJOR8RE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}