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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86678aa3481060989503e83685d73d621243501e63ca99d15b2ff53f2946a5b7' 
  AND token = 'kXZaswzTpksKyRyFqExaaM2b1kJSQ9IDbIcrBZN4T6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}