SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c39e6066c8e0d77739808f6e9260cbda7220b9f91443c08708c0ceb868fed468' 
  AND token = '1RmOOmYumJfKtbO6Zpa0r97MTzpBfl8CbYz6yCX2ZSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}