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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5aeeeb227dfe87cbd3c4e96435085c9679e89ea4b33f059e054e2b78ac07ad9a' 
  AND token = 'Z7+YS0rsbRE4bPYORJRB1itl1L6bUfF6vYMTdlTr4bs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}