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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45fa98cb058f9d9f654c92ad94e2e99d805e7a3ecb18c462bc34e14709f306af' 
  AND token = 'fYjARB940WnhjW463zeO7Q76wv7AgVC4N4f46uMKp9w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}