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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8f4f54f2eff04ba21531817445f917f0bf991afc7209f818208ce7590ace776' 
  AND token = '7n+IZlycwBVIwtjRsU7uP2s8px7nsCtOrsbFAp7868U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}