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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c97d5ba90618385f7172452c36ea8e8310089d6ee6868494e0b7bb04e5b05462' 
  AND token = '+1/yU38NXmonQEqsrJANglHrXlKwQAAv6G6q625IcJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}