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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4d9df7f59e5a50e3424b58920b4b46a950d5defc693adf136b984581746ff21' 
  AND token = '+LrQFD2Sj691tCJAU1sJAr+wCxVJgEXA7/SOulVnrPE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}