SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a597e2907ac9db3417e1fc371774d5a10193e06c3775407c7b0d8fc38b19101' 
  AND token = '2ymJ1bqDAGI5gObTxIYzTKAz3yFGpyMs6XnnsIpVHIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}