SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f65ac0f6e410c6a0bf7d822afdfb02574298d7b86d44da0613f33afec700bc7' 
  AND token = 'wkyaJDGTTHVOQF+LtDx2iNXtKe4RDLECet9uBLvQVoQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}