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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e693bcc672ba678fbefe07a13721ca104eae7bee533352a51046afd07070f0f' 
  AND token = 'iYwjf+TDp6btdQhhzjD2dZnQji/4f1itLqB2FeQb5iI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00078

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}