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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e40f920fe9a9d3fc9ae95a87b03f64837a324cff722bba0fd91e74370db2175' 
  AND token = 'nSL9SQFmcQbVTlwEGKH7P0u3v4GLB8bGMXl0saW+jaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}