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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b33c90fab06b84b1f169dabb4a0777a88469fc062ecd0c08e49653c07219635' 
  AND token = 'hD9uWAx1/giBbiFN3y8Mh0sONZ9GCOkMIf0lmbx/R8w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}