SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e78d3e541d6403c565d46f160279e8b2fb7b0791b07927766e3beabdf2495fd3' 
  AND token = 'CA5ZZg47Yv18O75ZzsBms1IcjMD/Pc1uquccLnr6bWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}