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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd78f2fddb6752cdce35a22b255416d99795bb70285eb092ea02ce2459c517ccc' 
  AND token = 'W/6DmrBtBDD/1LpCg+G5ib30KzpOi47SFHEbC6eTlFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}