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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6db49826a85c2ea75397db0394a0aa82531842554a9eb634d0163430640d8a58' 
  AND token = '4LkDvhwprVagZCRPfNtO9j8M1+6aCGzhMy1ZHG0nHiA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}