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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '178efa5879ad09ab470f6fa8df2b35e6a330513fe13732a7b07bbb92e7a2cb68' 
  AND token = 'jvoCrSOWr2pX+aQbu2JN+ixiWaO7Ng+o2j4toQKn2P4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}