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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5079d7e4adc5b0dc3e1fe820f3df03c6356d2d76e202e5d540fa457c280733dc' 
  AND token = 'Ls2sRdYn8RXgae+sE5i683o08B797JO12YsPOQGRJFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}