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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec5648a7da339bcf4c53367e73f67374f759d70dc085c899b1e62389c6a5df8d' 
  AND token = 'xIuZvAxEAqhK80UC4AvmjI41m7aftH5XHyS2gLtzca4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}