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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0636c536a42c1c1e5325b64b8e05987c41c3422018ec92d0a09ff35f3791e9a' 
  AND token = 'QUW+auNaws+vFt0UHKtw7AKeMvxJMr6ToKzMf8U1wyo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}