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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8877d94f501c140b96b20d9b3d73eb353ca1174af9f50f572de1cd7e1e1de95d' 
  AND token = 'pN02TOdQDkuV/I220N5Xtq8uzdM3K0eBDFGpcf3mQ8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}