SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77dfe76720a878dbf82be120e4dd5c32ac931e95c04c3b7802996bccac9085a2' 
  AND token = '5SULe8i0QVjueGz4ev+kS+DZLQGHi2O+gh0FEDVsAMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}