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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3444ad8c861782e52991e37641049ecaa8e73d82b8d75d6c366ca56dd5fe8c36' 
  AND token = 'TLCYsbdB1H1JwyoVPuJSWTYDBbQ3INo+iNW6U28FO1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}