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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51ad7d6de4a0b0fd83900e3b825778932729df4b8ec83f60cc4d50d32f52f816' 
  AND token = 'FS/ue19dVcdzvfH9hdD7uJi/Aelw8TSQA9fVN29pdCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}