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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cf17e4c002904c633fc80d4ae39e8854f5cb19ac1d0037c145a72b76056736d' 
  AND token = '/T53DuBqHIokF4Aa1DAUQKAvy9scUkP+jya2+A/3fCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}