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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c0574a260a998e93017fa44b835a0e486cac1f9a3c55aa8e1ef4db1b947a457' 
  AND token = 'zwhzE6R2BcHBicgwwSE+0lwRF8vFMCS02ooK5KGi1tE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}