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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b3936df76956642232341d3e948215f1e8a4288db71939c885dc88882d088a4' 
  AND token = 'DiF8F2TxrWXHkqiPZF+xfqNH0bDWWwRTfshYllAFXjE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}