SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8e09319f56ee552df830ed7d23941b4f3d587d8f3f82634d82b6b660488c326' 
  AND token = 'XYEVG+BHh8yPms5egeTliXm5XxSxGkrEwcWPhQYW5Ds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}