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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '672e3437e0e2982ad29fe1aeef47c9ba01c0fec38388a89af020d3de8906f127' 
  AND token = 'jkSQghndDUk68VqDurLcfxOAvj7QSzxmgoD6/EqFjaI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}