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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03a2aea60ed66159ec8b4d616564771b5d336985751ee9cc8dc850500ddf3eb4' 
  AND token = 'yD6XTB3EXHE0wxQQAkA8JgfIL/OMB0kiVxhZyDWfXUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}