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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20e5ab2d57e663c39822b4d8363a857ff220ab71aeb29087223e734c73aa0d03' 
  AND token = 'ArN2+sQAGxN8NdplHBcQ9dkxrrNZlI/TTx0vqNxiRDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}