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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e51eac2dc28374248d96f4daeaed50dbd651868c240dfa163c3d1bc69c45dc19' 
  AND token = 'Bum+TsMviWw9HZc5fYQa5/lhc2yaMQrEpPNYw4HK3rM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}