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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b43e4ceb2934ec61b1b09eec9dd893d2b01f3a7891a7f895f9494382db6e980' 
  AND token = 'Ovm1FyplXAhWh8ISCfehsxrEs2cxT0U1wgeV6BFAS7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}