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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa4b4ff4626cceba99da5e4869ad0d2708e999419503c90022a68323e3cd3aad' 
  AND token = 'HkXoA/xRl2GPVC/EU5Cbe5ifNYA7OMccWO45L0cs8Yo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}