SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '105133f0137d3cab3a39e4d34f6056477e300ac5bc2347f90b256f68820cc6ab' 
  AND token = 'ugGKtVswbN+JOtWSUThPkjitFHrmH8gVp/YtiM2hC+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}